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KMID : 1202020080010010029
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Journal of Korean Thyroid Association
2008 Volume.1 No. 1 p.29 ~ p.32
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Can Topical Hemostatic Agent Reduce the Amount of Post-operative Drainage of Total Thyroidectomy with Central Neck Dissection
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Kim Ho-Chan
Choi Seung-Ho
Kim Sang-Yoon
Nam Soon-Yuhl
Roh Jong-Lyel
Lim Gil-Chai
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Abstract
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Background and Objectives: The amount of postoperative drainage is important factor to decide hospitalization and medical expense. The purpose of this study was to verify the advantage of using topical hemostatic agents after total thyroidectomy with central neck dissection (CND) to reduce postoperative drainage.
Materials and Methods: From Jun 2007 to March 2008, 79 patients underwent total thyroidectomy with CND by one surgeon. Before wound closure, the operative bed was covered with fibrin sealant (group A, Beriplast?; n=22), microfibrillar collagen (group B, Avitene?; n=30) or nothing (group C, control; n=27). The amount of drainage was measured every 24 hours until drain removal. The drainage amount, hospital stay, and total medical expense were compared among the 3 groups by T-test.
Results: The drainage amount for group A, B and C was 43.4 ml, 48.5 ml, 49.7 ml on the first postoperative day, 41.9 ml, 48.5 ml, 49.7 ml on the second day, 16.3 ml, 21.8 ml, 20.2 ml on the third day, respectively, resulting in no significant difference (p=0.08∼0.8). Hospital stay was not different among 3 groups. Total medical expense for group A,B and C was 2,602,118 Korean Won (KRW), 2,657,255 KRW, 2,496,647 KRW, respectively, which showed significantly lower medical expense in group C than group A or B.
Conclusion: Topical hemostatic agents are not helpful to reduce the amount of the postoperative drainage and medical expense in cases of total thyroidectomy with CND.
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KEYWORD
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Hemostatic, Fibrin, sealant, Avitene
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